Yiping Tu Selected Research

Lamin Type B (Lamin B)

1/2021	Nuclear membrane ruptures underlie the vascular pathology in a mouse model of Hutchinson-Gilford progeria syndrome.
12/2019	An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death.
5/2013	Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration.
12/2011	Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons.
3/2010	Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.

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Yiping Tu Research Topics

Disease

9	Progeria (Hutchinson Gilford Syndrome) 01/2021 - 03/2010
4	Rupture 01/2021 - 10/2018
2	Blister (Bulla) 10/2018 - 12/2011
2	Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris) 11/2017 - 02/2016
2	Lipodystrophy 09/2016 - 03/2010
2	Inborn Genetic Diseases (Disease, Hereditary) 05/2015 - 09/2011
1	Atherosclerotic Plaque (Atheroma) 01/2019
1	Glioma (Gliomas) 01/2019
1	Hypertriglyceridemia 01/2019
1	Premature Aging 01/2018
1	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 01/2017
1	Vascular Diseases (Vascular Disease) 01/2017
1	Familial Partial Lipodystrophy (Dunnigan Syndrome) 09/2016
1	Esophageal Achalasia (Megaesophagus) 05/2015
1	Ichthyosis (Xeroderma) 12/2014
1	Obesity 06/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2014
1	Insulin Resistance 01/2013
1	Hyperbilirubinemia 01/2012
1	Cardiomyopathies (Cardiomyopathy) 07/2010
1	Neoplasms (Cancer) 04/2010
1	Lissencephaly 03/2010
1	Muscular Dystrophies (Muscular Dystrophy) 03/2010
1	Atherosclerosis 01/2010

Drug/Important Bio-Agent (IBA)

7	LaminsIBA 01/2021 - 03/2010
6	prelamin AIBA 01/2018 - 07/2010
5	Lamin Type B (Lamin B)IBA 01/2021 - 03/2010
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2017
3	LipidsIBA 01/2019 - 01/2010
3	Lamin Type A (Lamin A)IBA 09/2016 - 07/2010
3	lamin CIBA 09/2016 - 07/2010
2	ChromatinIBA 01/2021 - 12/2014
2	Lipoproteins (Lipoprotein)IBA 01/2019 - 01/2010
2	geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA 01/2012 - 04/2010
1	Small Interfering RNA (siRNA)IBA 01/2021
1	SiliconIBA 12/2019
1	CholesterolIBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	high density lipoprotein binding proteinIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2017
1	AntibodiesIBA 09/2016
1	Lopinavir FDA Link 09/2016
1	Monoclonal AntibodiesIBA 09/2016
1	Nonsense Codon (Nonsense Mutation)IBA 02/2016
1	Insulin (Novolin)FDA Link 01/2013
1	MethyltransferasesIBA 01/2013
1	Transaminases (Aminotransferases)IBA 01/2012
1	EnzymesIBA 04/2010